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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Gene Ther. 2013 Jul 11;20(12):10.1038/gt.2013.40. doi: 10.1038/gt.2013.40

Figure 8.

Figure 8

CTL cytolytic activity. C57BL/6 male mice bearing subcutaneous TRAMP-C2 tumors were injected with saline, Ad5-yCD/mutTKSR39rep (5 × 108 PFU) or Ad5-yCD/mutTKSR39rep-mIL12 (5 × 108 PFU) on day 0. Animals were killed on days 0, 1, 2, 7 and 14 and spleenocytes were prepared. Specific lysis of IFN-γ stimulated TRAMP-C2 cells on day 7 was examined at varying E:T ratios (left). Specific lysis of TRAMP-C2 cells on various days after the adenovirus injection at an E:T ratio of 50 (right). The results represent the mean of three mice per data point ± s.d.