. Author manuscript; available in PMC: 2014 Mar 1.

Published in final edited form as: Gene Ther. 2013 Jul 11;20(12):10.1038/gt.2013.40. doi: 10.1038/gt.2013.40

Table 2. Immune cell depletion studies.

Groups	n	Median survival (days)	Tumor free (%)	Mets^a (%)
Saline	10	26^b	0	100
Ad5-yCD/mutTK_SR39rep-mIL12 + control IgG	20	>90^b	70	10
Ad5-yCD/mutTK_SR39rep-mIL12 + anti-NK/NKT	10	42^b	0	90
Ad5-yCD/mutTK_SR39rep-mIL12 + anti-CD4	10	73^b	0	70
Ad5-yCD/mutTK_SR39rep-mIL12 + anti-CD8	10	56^b	0	80

Abbreviations: IgG, immunoglobulin G; Mets, metastases.

Percent of animals with metastases at necropsy.

P<0.05 versus saline controls.