Figure 2.
RSK3 protein expression in pancreatic cancer. (A) RSK3 protein expression in various pancreatic cancer cell lines and the pancreatic ductal epithelial cell line HPDE, as assessed by Western blot analysis. (B) Representative immunohistochemical analysis of phospho-RSK3 (Thr356/Ser360) expression indicative of active RSK3 in human normal pancreatic tissue and pancreatic cancers. (C) RSK3 expression in murine pancreatic cancer tissue derived from the KPC mouse model, as assessed by immunohistochemistry using the phospho-RSK3 (Ser2218) antibody.