Figure 2.

N-Myc increases MXI1-0/MXI1 expression ratios in native MYCN-expressing NB cells. MYCN/β-actin and MXI1-0/MXI1 ratios in NB cell lines. Real-time RT-PCR was used to determine the copy number of MYCN, β-actin, MXI1-0, and MXI1 in a number of NB cell lines. The ratios of MYCN to β-actin (A) and MXI1-0 to MXI1 (B) were calculated and plotted. These ratios were plotted against each other (C), and linear regression was used to determine the correlation between these ratios (r² = 0.9359, P < .05).