Table 1.
Hour | 1st | 2nd | 3rd | 4th | 24th |
---|---|---|---|---|---|
Levetiracetam (mg/kg) |
|||||
Alcohol (IA) Drinkers | |||||
Vehicle | 0.23 ± 0.03 | 0.43 ± 0.05 | 0.64 ± 0.07 | 0.85 ± 0.07 | 3.13 ± 0.21 |
0.3 | 0.24 ± 0.08 | 0.51 ± 0.07 | 0.73 ± 0.07 | 0.99 ± 0.08 | 3.47 ± 0.20 |
3.0 | 0.36 ± 0.05 | 0.61 ± 0.08 | 0.85 ± 0.09 | 1.03 ± 0.08 | 3.33 ± 0.15 |
10.0 | 0.19 ± 0.05 | 0.57 ± 0.08 | 0.82 ± 0.10 | 1.05 ± 0.10 | 3.54 ± 0.25 |
30.0 | 0.29 ± 0.06 | 0.50 ± 0.06 | 0.68 ± 0.09 | 0.85 ± 0.07 | 3.34 ± 0.25 |
100.0 | 0.29 ± 0.05 | 0.61 ± 0.10 | 0.85 ± 0.10 | 1.04 ± 0.12 | 3.31 ± 0.39 |
Sucrose (IA) Drinkers | |||||
Vehicle | 0.18 ± 0.02 | 0.35 ± 0.04 | 0.52 ± 0.06 | 0.64 ± 0.07 | 2.18 ± 0.21 |
0.3 | 0.16 ± 0.06 | 0.27 ± 0.05 | 0.41 ± 0.07 | 0.59 ± 0.10 | 2.08 ± 0.40 |
3.0 | 0.13 ± 0.04 | 0.32 ± 0.06 | 0.41 ± 0.07 | 0.54 ± 0.10 | 1.75 ± 0.32 |
10.0 | 0.20 ± 0.04 | 0.30 ± 0.05 | 0.41 ± 0.07 | 0.50 ± 0.09 | 1.67 ± 0.35 |
30.0 | 0.18 ± 0.03 | 0.34 ± 0.04 | 0.48 ± 0.06 | 0.63 ± 0.09 | 1.60 ± 0.25 |
100.0 | 0.20 ± 0.05 | 0.53 ± 0.15 | 0.63 ± 0.10 | 0.93 ± 0.20 | 2.30 ± 0.27 |
All data are expressed as mean ± SEM