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(b) 10 best 5 bp motifs in always methylated regions
| Pattern | MEME detail positive or negative strand | Our software always methylated |
|---|---|---|
| AGGGG | FXN_AM_1++FMR1+−− | FMR1+−−FXN_AM_1++ |
| CCAGC | FXN_AM_1−FMR1− | FMR1+−−FXN_AM_1− |
| CTGGC | FXN_AM_2+FMR1+ | FMR1+++FXN+ |
| CCACC | FXN_AM_2−FMR1+ | FMR1++FXN_AM_2− |
| CCTCA | FMR1− − | FMR1+− − − |
| CCGCC | FXN_AM_1−FMR1+ | FXN_AM_1−FMR1+ |
| AGCAC | FXN_AM_2−FMR1− | FXN_AM_2−FMR1+++− |
| AGTTG | FMR1++ | FMR1+++FMR1− − |
| TAGCA | FMR1−FMR+ | FMR1++ − − |
| AGAAA | FXN_AM_2+FMR1++−−− − | FXN_AM_2+FMR1++−−− − |
