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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Gastroenterology. 2013 Jul 31;145(5):10.1053/j.gastro.2013.07.044. doi: 10.1053/j.gastro.2013.07.044

Figure 5. Most vaccine-induced CD4 T cells are terminally differentiated whereas most exposure-induced CD4 T cells are effector memory cells.

Figure 5

(A) Gating strategy. (B) Percentage of terminally differentiated effector T cells (CD45RO−CCR7−CD127−) and effector memory T cells (CD45RO+CCR7−CD127−) within the CD69+IFN-γ+ CD4 T cell population after stimulation with either HBs or HBcore/pol-peptides. Mean ± SEM of data from 36 vaccinees and from 13 patients recovered from acute HBV are shown. Statistical analysis: unpaired t-test.