Table 4.
AKIN48 (n=82) | P | RIFLE24 (n=27) | P | Dialysis (n=12) | P | |
---|---|---|---|---|---|---|
GGT/uCr | 0.57 (0.50–0.64) | 0.058 | 0.61 (0.49–0.73) | 0.062 | 0.63 (0.46–0.81) | 0.13 |
AP/uCr | 0.56 (0.49–0.63) | 0.11 | 0.64 (0.52–0.76) | 0.018 | 0.72 (0.55–0.88) | 0.010 |
CysC/uCr | 0.55 (0.48–0.62) | 0.18 | 0.63 (0.51–0.74) | 0.004 | 0.66 (0.49–0.83) | 0.070 |
NGAL/uCr | 0.55 (0.48–0.63) | 0.17 | 0.68 (0.56–0.80) | 0.003 | 0.78 (0.61–0.95) | 0.001 |
IL-18/uCr | 0.55 (0.47–0.62) | 0.21 | 0.72 (0.61–0.83)b | <0.0001 | 0.70 (0.53–0.87) | 0.020 |
KIM-1/uCr | 0.55 (0.47–0.62) | 0.21 | 0.64 (0.52–0.76) | 0.018 | 0.63 (0.45–0.80) | 0.15 |
Abbreviations: AKI, acute kidney injury; AKIN48, AKI within 48 h; AP, alkaline phosphatase; AUC, area under the receiver operator characteristic curve; CysC, cystatin C; GGT, γ-glutamyltranspeptidase; IL-18, interleukin-18; KIM-1, kidney injury molecule-1; NGAL, neutrophil-gelatinase-associated lipocalin; uCr, urinary creatinine.
n=381.
RIFLE24: significantly higher than the AUC for CysC/uCr.