. Author manuscript; available in PMC: 2014 Jan 8.

Published in final edited form as: Kidney Int. 2011 Feb 9;79(10):10.1038/ki.2010.555. doi: 10.1038/ki.2010.555

Table 4.

AUCs for prediction of AKI and dialysis in patients without AKI on entry^a

	AKIN48 (n=82)	P	RIFLE24 (n=27)	P	Dialysis (n=12)	P
GGT/uCr	0.57 (0.50–0.64)	0.058	0.61 (0.49–0.73)	0.062	0.63 (0.46–0.81)	0.13
AP/uCr	0.56 (0.49–0.63)	0.11	0.64 (0.52–0.76)	0.018	0.72 (0.55–0.88)	0.010
CysC/uCr	0.55 (0.48–0.62)	0.18	0.63 (0.51–0.74)	0.004	0.66 (0.49–0.83)	0.070
NGAL/uCr	0.55 (0.48–0.63)	0.17	0.68 (0.56–0.80)	0.003	0.78 (0.61–0.95)	0.001
IL-18/uCr	0.55 (0.47–0.62)	0.21	0.72 (0.61–0.83)^b	<0.0001	0.70 (0.53–0.87)	0.020
KIM-1/uCr	0.55 (0.47–0.62)	0.21	0.64 (0.52–0.76)	0.018	0.63 (0.45–0.80)	0.15

Abbreviations: AKI, acute kidney injury; AKIN48, AKI within 48 h; AP, alkaline phosphatase; AUC, area under the receiver operator characteristic curve; CysC, cystatin C; GGT, γ-glutamyltranspeptidase; IL-18, interleukin-18; KIM-1, kidney injury molecule-1; NGAL, neutrophil-gelatinase-associated lipocalin; uCr, urinary creatinine.

n=381.

RIFLE24: significantly higher than the AUC for CysC/uCr.