. Author manuscript; available in PMC: 2014 Jan 8.

Published in final edited form as: Ann Surg Oncol. 2011 Nov 3;19(4):10.1245/s10434-011-2125-1. doi: 10.1245/s10434-011-2125-1

Table 3.

Correlation analysis between the combined expression status of MUC13m, CDH17, LGALS4, REG4 and clinicopathologic parameters.

Biomarkers		CDH17		REG4		LGALS4		MUC13m

Expression		+	−	+	−	+	−	+	−
Age		58.0±12.8	56.8±12.6	59.2±12.1^*	56.6±13.2^*	57.6±12.4	58.3±13.1	61.4±11.5^*	54.6±12.8^*
Sex	M:F	2.3:1	3.3:1	2.4:1	2.8:1	2.3:1	3.1:1	3.7:1^*	2.1:1^*
Differentiation	Undifferentiated	139 (55.4%)^*	112 (44.6%)^*	106 (47.5%)	117 (52.5%)	131 (58.0%)	95 (42.0%)	43 (17.4%)^*	204 (82.6%)^*
Lauren	diffuse	98 (54.1%)^*	83 (45.9%)^*	75 (46.6%)^*	86 (53.4%)^*	95 (58.3%)	68 (41.7%)	15 (8.4%)^*	164 (91.6%)^*
Lymphatic invasion		151 (58.5%)	107 (41.5%)	117 (48.1%)	126 (51.9%)	123 (50.2%)^*	122 (49.8%)^*	105 (41.2%)	150 (58.8%)
Venous invasion		47 (62.7%)	28 (37.3%)	33 (45.2%)	40 (54.8%)	35 (47.9%)	38 (52.1%)	35 (47.3%)	39 (52.7%)
Perineural invasion		124 (58.5%)	88 (41.5%)	88 (44.0%)^*	112 (56.0%)^*	113 (56.2%)	88 (43.8%)	67 (31.9%)^*	143 (68.1%)^*
T stage
	T1	45 (36.3%)	79 (63.7%)	39 (39.4%)^†	60 (60.6%)^†	38 (36.5%)	66 (63.5%)	51 (41.8%)^††	71 (58.2%)^††
	T2	23 (33.3%)	46 (66.7%)	35 (53.0%)^†	31 (47.0%)^†	34 (50.7%)	33 (49.3%)	39 (58.2%)^††	28 (41.8%)^††
	T3	57 (37.7%)	94 (62.3%)	74 (52.5%)^†	67 (47.5%)^†	60 (42.6%)	81 (57.4%)	85 (57.0%)^††	64 (43.0%)^††
	T4	46 (47.9%)	50 (52.1%)	52 (56.5%)^†	40 (43.5%)^†	45 (48.9%)	47 (51.1%)	67 (70.5%)^††	28 (29.5%)^††
N stage
	N0	68 (36.6%)	118 (63.4%)	72 (45.6%)	86 (54.4%)	59 (36.2%)^††	104 (63.8%)^††	93 (51.1%)^†	89 (48.9%)^†
	N1	21 (33.3%)	42 (66.7%)	32 (54.2%)	27 (45.8%)	28 (46.7%)^††	32 (53.3%)^††	32 (52.5%)^†	29 (47.5%)^†
	N2	20 (33.9%)	39 (66.1%)	24 (41.4%)	34 (58.6%)	24 (41.4%)^††	34 (58.6%)^††	32 (54.2%)^†	27 (45.8%)^†
	N3	62 (47.0%)	70 (53.0%)	72 (58.5%)	51 (41.5%)	66 (53.7%)^††	57 (46.3%)^††	85 (64.9%)^†	46 (35.1%)^†
M stage	M0	149 (38.5%)	238 (61.5%)	167 (48.1%)^†	180 (51.9%)^†	146 (41.4%)^††	207 (58.6%)^††	206 (54.1%)^†	175 (45.9%)^†
	M1	22 (41.5%)	31 (58.5%)	33 (64.7%)^†	18 (35.3%)^†	31 (60.8%)^††	20 (39.2%)^††	36 (69.2%)^†	16 (30.8%)^†

MUC13m indicates membranous type MUC13.

P<0.05

^†

Pearson's correlation is significant at the 0.05 level

^††

Pearson's correlation is significant at the 0.01 level