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. 2013 Aug 14;34(9):1260–1268. doi: 10.1002/humu.22358

Figure 1.

Figure 1

Sequential COX–SDH histochemistry. Sequential cytochrome c oxidase (COX) and succinate dehydrogenase (SDH) histochemistry was performed on skeletal muscle biopsies from all patients with the exception of patients 1 and 6. A mosaic pattern of COX activity is visible in each of the images, with COX-deficient fibers shown in blue and COX-positive fibers shown in brown. For patient 6, the individual COX histochemical reaction demonstrates a large number of COX-deficient fibers.