TABLE 2.
In Vivo Bronchoalveolar Lavage Parameters of rats 24 hours after intratracheal instillation of 100 μg of NPs (25 μg of copper NP). Values represent the mean of 3 - 5 animals; standard deviations are shown in parentheses.
| Total Cells ×107 |
% Mac | %PMN | % Lymph | % Viable | Protein mg/mL |
LDH nmol/mL/min |
β-gluc nmol/mL/min |
|
|---|---|---|---|---|---|---|---|---|
| Saline |
1.597
(0.190) |
98.1
(0.4) |
1.1
(0.5) |
1.1
(0.6) |
95.6
(1.1) |
0.154
(0.007) |
59.668
(9.232) |
0.367
(0.060) |
| TiO2(D) |
1.488
(0.019) |
86.7
(2.0) |
12.0
(2.0) |
1.4
(0.2) |
96.2
(0.5) |
0.122
(0.015) |
67.574
(4.786) |
0.142
(0.015) |
| TiO2(F) |
1.091
(0.143) |
94.63
(2.4) |
4.4
(2.7) |
1.2
(0.4) |
92.7
(1.0) |
0.186
(0.008) |
52.250
(2.461) |
0.311
(0.006) |
| TiO2(M) |
1.473
(0.118) |
95.4
(3.9) |
3.3
(3.5) |
1.3
(0.63) |
96.1
(1.0) |
0.116
(0.005) |
60.895
(6.237) |
0.311
(0.036) |
| Ag |
2.269
(0.238) |
65.2
(8.7) |
33.8
(8.9) |
1.0
(0.5) |
97.1
(0.5) |
0.237
(0.028) |
105.233
(16.166) |
0.998
(0.260) |
| Cu |
2.706
(0.951) |
47.5
(10.9) |
50.8
(10.5) |
1.8
(0.6) |
95.3
(0.8) |
0.696
(0.243) |
191.592
(52.413) |
2.861
(0.758) |
| Au |
1.545
(0.332) |
96.2
(2.2) |
2.8
(1.6) |
0.9
(0.6) |
93.2
(2.7) |
0.188
(0.010) |
76.916
(8.462) |
0.316
(0.010) |
| C |
1.845
(0.288) |
75.3
(7.5) |
22.4
(6.1) |
2.4
(2.1) |
96.1
(0.4) |
0.218
(0.024) |
115.658
(8.274) |
0.688
(0.086) |
| PS-NH3 |
1.591
(0.167) |
95.3
(2.0) |
3.9
(1.8) |
0.8
(0.4) |
94.5
(1.6) |
0.153
(0.009) |
76.848
(7.668) |
0.331
(0.057) |