Table 3.
Multivariate Model for Risk of Mastectomy
| Hazard Ratio | 95% CI | P-value | |
|---|---|---|---|
| Receipt of Radiation Therapy | |||
| No | 1 | ||
| Yes | 0.33 | (0.22–0.48) | <.001 |
| Age | |||
| 70–74 | 1 | ||
| 75–79 | 0.61 | (0.45–0.84) | 0.002 |
| Race | |||
| White | 1 | ||
| Hispanic | 1.63 | (0.52–5.12) | 0.404 |
| Black | 2.32 | (1.39–3.86) | 0.001 |
| Asian | 0.27 | (0.04–1.95) | 0.196 |
| Other/Unknown | 0.46 | (0.07–3.31) | 0.442 |
| Comorbidity | |||
| 0 | 1 | ||
| 1 | 0.92 | (0.63–1.34) | 0.651 |
| 2 or more | 1.24 | (0.79–1.93) | 0.348 |
| Unknown | 0.69 | (0.28–1.72) | 0.425 |
| Year of diagnosis | |||
| 1992 – 1995 | 1 | ||
| 1996 – 1999 | 0.87 | (0.60–1.26) | 0.460 |
| 2000 – 2002 | 0.93 | (0.63–1.39) | 0.728 |
| Tumor histology | |||
| Invasive ductal/other | 1 | ||
| Invasive lobular | 0.49 | (0.23–1.05) | 0.067 |
| Tumor Grade | |||
| Low/Intermediate/Unknown | 1 | ||
| High | 1.79 | (1.24–2.58) | 0.002 |
| Receipt of chemotherapy | |||
| No | 1 | ||
| Yes | 0.90 | (0.42–1.91) | 0.775 |
| Axillary lymph node status | |||
| Clinical node negative | 1 | ||
| Pathologic node negative | 1.28 | (0.88–1.85) | 0.195 |
Abbreviations: RT (Radiation therapy), CI (Confidence interval)