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. Author manuscript; available in PMC: 2015 Jan 15.
Published in final edited form as: J Immunol. 2013 Dec 13;192(2):10.4049/jimmunol.1301434. doi: 10.4049/jimmunol.1301434

FIGURE 6.

FIGURE 6

NaAsO2 and As2O3 inhibit inflammasomes in vivo. (A) Inflammatory cell recruitment was assessed after 2 h in the peritoneum of Balb/cJ mice injected i.p. with MSU (0.5 mg/250 μl/mouse). Mice had been injected with either PBS (i.p.) or As2O3 (1.25 mg/kg, i.p.). Error bars represent standard error of the mean. n = 5 animals/group. P = 0.0291. (B) Fischer rats pretreated with 7 mg/kg As2O3 i.v. (n=7) or 5 mg/kg NaAsO2 i.v. (n=7) were challenged with LT (12 μg, i.v.). Times to death (one symbol representing one animal) were compared to control animals that did not receive drug treatment (n=5). P-values comparing each treatment group to controls are <0.0075.