Table III.
Literature on the use of negative pressure wound therapy (NPWT) on closed abdominal, plastic and vascular incisions
| Authors | Study type* | Indication | Results† | Negative pressure delivery and use‡ | ||||
|---|---|---|---|---|---|---|---|---|
| López-Cano and Armengol-Carrasco26 | NC | Incisional hernia repair: n = 3 NPWT | No infections or seroma | tNPWT wide-field PU foam -125 mmHg; 5 days | ||||
| Condé-Green et al27 | CC | Incisional hernia repair: n = 33 vs n = 23 NPWT | Wound complication: 63.6% vs 22% (p = 0.02). Skin dehiscence: 39% vs 9% (p = 0.014) | tNPWT PU foam -125 mmHg; 5 days | ||||
| Dutton and Curtis28 | Single case | High-risk abdominal incision: n = 1 NPWT | - | tNPWT PU foam, -75/-100 mmHg; 7 to 10 days | ||||
| Schmedes et al32 | CC | Skin flap donor site closures: n = 42 vs n = 52 NPWT | Major complication: 12% vs 5.8% (NS) | tNPWT PU foam, -175 mmHg; 14 to 16 days | ||||
| Masden et al37 | RCT | High-risk primary or delayed primary lower extremity closures: n = 37 vs n = 44 NPWT | Infection: 13.5% vs 6.8% (NS). Dehiscence: 29.7% vs 36.4% (NS) | tNPWT PU foam -125 mmHg; 3 days | ||||
| Haghshenasskashani and Varcoe33 | Single case | High-risk incision following vascular graft: n = 1 | - | suNPWT PU foam -125 mmHg; 5 days | ||||
| Vargo29 | NC | High-risk abdominal closure: n = 30 | No infections | tNPWT PU foam -75 mmHg; mean 5.6 days | ||||
| Blackham et al30 | CC | High-risk abdominal oncology: n = 87 vs n = 104 NPWT | Infection: 35.5% vs 16.0% (p = 0.011) | tNPWT PU foam -125 mmHg; 4 days | ||||
| Bollero et al35 | NC | Scar excision and closure: n = 8 | No complications | suNPWT foam -125 mmHg; 8 days | ||||
| Pauli et al31 | CC | High-risk ventral hernia repair: n = 70 vs n = 49 NPWT | Infection: 25.8% vs 20.4% (p = 0.50) | tNPWT PU foam -75 mmHg; 7 days | ||||
| Matatov et al34 | CC | Femoral vascular procedures: n = 63 vs n = 52 NPWT | Infection: 30% vs 6% (p = 0.001) | suNPWT foam -125 mmHg; 5 to 7 days | ||||
| Tauber et al36 | CC | Inguinal lymph node dissection closures: n = 30 vs n = 15 NPWT | Intervention for complications: 23% vs 7% (p = 0.63) | tNPWT PVA foam; -100 mmHg; up to 7 days | ||||
* NC, non-comparative case series; CC, comparative cohort; RCT, randomised controlled trial † NS, not significant ‡ tNPWT, traditional NPWT (durable NPWT pump); suNPWT, single-use NPWT; PU, polyurethane; PVA, polyvinyl alcohol