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. 2013 Jun 11;55(1):105–112. doi: 10.1093/jrr/rrt080

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© The Author 2013. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Therapeutic Radiology and Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — The box plot and ROC curve of V5 relative to the development of Grade 0–1 and Grade 2–3 RP. (a) The box plot shows that the values of the mean ± standard deviation for V5 were (65.65 ± 24.02)% and (87.73 ± 7.47)% for Grade 0–1 and Grade 2–3 RP, respectively. This difference was statistically significant in both univariate (P = 0.003) and multivariate analysis (P = 0.019). (b) The ROC curve of V5 yielded 0.780 of the AUC (area under curve), and this was statistically significant (P = 0.004). V5 was the most powerful predictor of the pulmonary dosimetric parameters, including mean lung dose and Vn (volume of percentage of tumor-free normal lung receiving ≥n Gy).