Table 1.
Patient characteristics (n = 45)
| Number of patients (%) | Incidence of RP (%) |
Statistical significance | |||
|---|---|---|---|---|---|
| Grade 0–1 | Grade 2–3 | ||||
| Age (years) | Median 53 | Median 52.5 | Median 59.0 | ns | |
| Range 33–81 | |||||
| Sex | Male | 24 (53.3) | 19 (42.2) | 5 (11.1) | ns |
| Female | 21 (46.7) | 14 (31.1) | 7 (15.6) | ||
| ECOG | 0, 1 | 37 (82.2) | 30 (66.7) | 7 (15.6) | ns |
| 2 | 8 (17.8) | 3 (6.6) | 5 (11.1) | ||
| Previous RT | yes | 5 (11.1) | 5 (11.1) | 0 | ns |
| no | 40 (88.9) | 28 (62.2) | 12 (26.7) | ||
| Previous CTx | yes | 20 (44.4) | 14 (31.1) | 6 (13.35) | ns |
| no | 25 (55.6) | 19 (42.2) | 6 (13.35) | ||
| Number | ≤5 | 31 (75.6) | 21 (46.6) | 8 (17.8) | ns |
| of lesions | >5 | 14 (24.4) | 12 (26.7) | 4 (8.9) | |
| Sum of PTV | ≤200 ml | 23 (53.3) | 19 (42.2) | 4 (8.9) | ns |
| volume | >200 ml | 22 (46.7) | 14 (31.1) | 8 (17.8) | |
| Daily/Total dose | <5.0/50 | 19 (42.2) | 14 (31.1) | 5 (11.1) | ns |
| (Gy) | ≥5.0/50 | 26 (57.8) | 19 (42.2) | 7 (15.6) | |
| PFT FVC (% of predictive value) | Median 93.1 | Median 114.0 | ns | ||
| FEV1 (% of predictive value) | Median 89.7 | Median 106.3 | |||
| DLCO (% of predictive value) | Median 67.6 | Median 68.0 | |||
RP = radiation pneumonitis, ECOG = Eastern Cooperative Oncology Group, RT = radiotherapy, CTx = chemotherapy, PTV = planning target volume, PFT = pulmonary function test, FVC = forced vital capacity, FEV1 = forced expiratory volume for 1 s, DLCO = diffusion capacity of carbon monoxide.