. 2013 Jun 11;55(1):105–112. doi: 10.1093/jrr/rrt080

Table 2.

Analysis of relationship between pulmonary dosimetric parameters and development of ≥Grade two radiation pneumonitis

		Mean	SD	Univariate	ROC		Multivariate
		Mean	SD	Univariate	AUC	P-value	Multivariate
V5	Grade 0–1	65.65	24.02	0.003	0.780	0.004	0.019
V5	Grade 2–3	87.75	7.47	0.003	0.780	0.004	0.019
V10	Grade 0–1	46.58	25.07	0.026	0.707	0.035	0.164
V10	Grade 2–3	64.42	15.50	0.026	0.707	0.035	0.164
V15	Grade 0–1	29.12	16.60	0.026	0.710	0.033	0.674
V15	Grade 2–3	41.45	13.33	0.026	0.710	0.033	0.674
V20	Grade 0–1	18.06	9.43	0.027	0.682	0.065	0.674
V20	Grade 2–3	25.69	11.11	0.027	0.682	0.065	0.674
V25	Grade 0–1	12.12	6.87	0.015	0.707	0.035	0.579
V25	Grade 2–3	17.51	7.21	0.015	0.707	0.035	0.579
V30	Grade 0–1	8.02	5.28	0.083	0.734	0.018
V30	Grade 2–3	12.74	6.13	0.083	0.734	0.018
V40	Grade 0–1	3.71	3.36	0.364	0.595	0.336
V40	Grade 2–3	4.82	4.23	0.364	0.595	0.336
V50	Grade 0–1	0.55	0.70	0.128	0.563	0.572
V50	Grade 2–3	1.01	1.22	0.128	0.563	0.572
MLD	Grade 0–1	11.53	4.67	0.006	0.758	0.009	0.512
MLD	Grade 2–3	15.71	2.88	0.006	0.758	0.009	0.512
NTCP	Grade 0–1	2.99	5.88	0.230	0.673	0.091
NTCP	Grade 2–3	6.30	11.66	0.230	0.673	0.091

SD = standard deviation, ROC = receiver observer curve, AUC = area under curve, V5–25 = volume percentage of tumor-free normal lung receiving at least 5–25Gy, MLD = mean lung dose, NTCP = normal tissue complication probability.