Table 3.
Literature review of developing radiation pneumonitis
| Authors | Primary/metastatic | RT technique | Incidence of symptomatic RP | Major contributor | Comments |
|---|---|---|---|---|---|
| Graham et al. [8] | primary | 3DCRT | 0–4% (V20 < 25%) | V20 | |
| 19–30% (V20 > 37%) | |||||
| Borst et al. [11] | primary | SBRT | 10.9% | MLD | |
| CFRT | 17.6% | ||||
| Guckenberger et al. [12] | primary and metastatic | SBRT | 18.6% | V2.5 | |
| Gopal et al. [13] | primary | CFRT | 60.9% (shortness of breath and exertional dyspnea) | V13 | threshold value of deteriorating DLCO |
| Yamashita et al. [14] | primary and metastatic | SBRT | 28% | irradiated lung volume- | larger volume of lung being irradiated to high dose |
| Song et al. [15] | primary | HT | 18% | V5 | ≥Grade 3 |
| Present study | metastatic | HT | 20.0% | V5 |
RT = radiation therapy, RP = radiation pneumonitis, CFRT = conventional fractionated radiation therapy, SBRT = stereotactic body radiotherapy, MLD = mean lung dose, DLCO = diffusion capacity of carbon monoxide, HT = helical tomotherapy.