Table 1.
Study Samples Collected From Normal and Dry Eye Subjects
| Evaluated Parametersf02 |
Study Subjects |
|||
|
MGD, Total
n
= 22 |
Normal Controls, Total
n
= 5 |
|||
|
Males,
n
= 7 |
Females,
n
= 15 |
Males,
n
= 1 |
Females,
n
= 4 |
|
| Age, y | 61.0 ± 8.6 | 57.8 ± 4.1 | 53 | 37.5 ± 3.5 |
| Tear production, mm | 8.0 ± 1.3 | 7.7 ± 0.6 | >10 | >10 |
| TBUT, s | 5.0 ± 1.7 | 4.5 ± 0.5 | >10 | >10 |
| Meibum score | 1.9 ± 0.2 | 2.6 ± 0.2 | 0 | 0 |
| Cornea stain positive | 7 | 2 | 0 | 0 |
| Telangiectasia positive | 7 | 4 | 0 | 0 |
| Tear film debris positive, slit lamp | 4 | 1 | 0 | 0 |
| Dark, nonmelting, nonbirefringent, nonlipid inclusions in meibum,* range | 0–4 | 0–2 | 0–1 | 0–1 |
TBUT, tear breakup time.
*
Evaluated in cross-polarized light using a 0 to 4 grading scheme as described and shown in Table 2.