TABLE 4. Average Sensitivity from Three Blinded Reviews of Single-Head and Dual-Head Molecular Breast Imaging as a Function of the Location of the Tumor Within the Breast.
Single Head |
Dual Heads |
|||||||
---|---|---|---|---|---|---|---|---|
Tumor Location | No. of Tumors | TP | FN | Sensitivity (%) |
TP | FN | Sensitivity (%) |
No. of Additional Tumors Detected with Dual Heads vs. Single Head Only |
| ||||||||
Upper outer quadrant | 48 | 41 | 7 | 85 | 45 | 3 | 94 | 4 |
Upper inner quadrant | 23 | 17 | 6 | 74 | 21 | 2 | 91 | 4 |
Lower outer quadrant | 15 | 12 | 3 | 80 | 13 | 2 | 87 | 1 |
Lower inner quadrant | 4 | 2 | 2 | 50 | 2 | 2 | 50 | 0 |
Superior midline | 9 | 6 | 3 | 67 | 7 | 2 | 78 | 1 |
Inferior midline | 7 | 6 | 1 | 86 | 7 | 0 | 100 | 1 |
Medial midline | 3 | 3 | 0 | 100 | 3 | 0 | 100 | 0 |
Lateral midline | 11 | 9 | 2 | 82 | 10 | 1 | 91 | 1 |
Subareolar and periareolar | 8 | 6 | 2 | 75 | 7 | 1 | 88 | 1 |
| ||||||||
Total | 128 | 102 | 26 | 80 | 115 | 13 | 90 | 13 |
Note—With single-head molecular breast imaging, detector 1 was used to image the inferior (in craniocaudal [CC] view) and lateral (in mediolateral oblique [MLO] view) aspects of the breast. With dual-head molecular breast imaging, detector 2 was used in addition to detector 1 to also image the superior (in CC view) and medial (in MLO) view of the breast. TP = true-positive, FN = false-negative.