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. Author manuscript; available in PMC: 2014 Jan 8.
Published in final edited form as: J Cell Biochem. 2010 Nov 1;111(4):10.1002/jcb.22786. doi: 10.1002/jcb.22786

Fig. 3.

Fig. 3

PKCδ siRNA enhances TRAIL-induced apoptosis: MCF-7/PKCδ cells were transfected with PKCδ siRNA or random siRNA alone for 72 h and then cells were treated with TRAIL for 4 h. A: Western blot shows PKCδ siRNA significantly reduces PKCδ, p-Akt levels, and enhances Bid cleavage, and PARP cleavage. Equivalent protein loading was assessed by stripping the membrane and re-probing with G3PDH antibody. Arrow indicates cleaved fragment. B: PKCδ inhibition by siRNA enhances TRAIL-induced apoptosis compared to random transfected cells in the presence of TRAIL.