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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: European J Org Chem. 2013 Jun 4;2013(20):10.1002/ejoc.201300643. doi: 10.1002/ejoc.201300643

Scheme 1.

Scheme 1

Retrosynthesis of marineosin A (1) and a functionalized spiroaminal lactam 8. TBDPS = tert-butyldiphenylsilyl, TIPS = triisopropylsilyl, Piv = pivalate, Bn = benzyl.