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. 2012 Dec 30;40(1):143–151. doi: 10.1093/schbul/sbs157

Table 1.

Risk Ratio Estimates (OR) for Schizophrenia and Affective Disorders Depending on IQ at Ages 7 and 11

IQ Groups (Group Mean) N Schizophrenia Affective Disorders
Risk (Number of Cases) Crude OR (95% CI) Adjusted ORa (95% CI) Risk (Number of Cases) Crude OR (95% CI) Adjusted ORb (95% CI)
Age 7 years 15 061 49 N = 14 167 N = 14 167
    <−2 SD<70 (63.5) 509 0.0157 (8) 8.40 (3.66–19.28) 7.89 (3.00–20.72) 0.0079 (4) 1.93 (0.69–5.40) 1.23 (0.36–4.26)
    <−1 SD70−84 (78.2) 1969 0.0081 (16) 4.31 (2.21–8.39) 2.72 (1.18–6.25) 0.0066 (13) 1.62 (0.86–3.02) 1.12 (0.54–2.34)
    <±1 SD85–115 (101.0) 10 017 0.0019 (19) 1.00 1.00 0.0041 (41) 1.00 1.00
    >+1 SD>115 (119.9) 2566 0.0023 (6) 1.23 (0.49–3.09) 1.18 (0.45–3.10) 0.0016 (4) 0.38 (0.14–1.06) 0.34 (0.10–1.09)
Age 11 years 14 1246 40 N = 13 880 N = 13 880
    <−2 SD<70 (65.8) 206 0.0194 (4) 10.69 (3.57–32.05) 9.01 (2.75–29.50) 0.0097 (2) 2.43 (0.58–10.13) 1.64 (0.38–7.14)
    <−1 SD70−84 (79.1) 2121 0.0056 (12) 3.07 (1.47–6.44) 2.51 (1.10–5.75) 0.0061 (13) 1.53 (0.81–2.882) 1.16 (0.59–2.28)
    <±1 SD85–115 (99.1) 9193 0.0018 (17) 1.00 1.00 0.0040 (37) 1.00 1.00
    >+1 SD>115 (121.7) 2726 0.0025 (7) 1.39 (0.58–3.35) 1.27 (0.49–3.29) 0.0022 (6) 0.55 (0.23–1.30) 0.69 (0.29–1.66)

Note: BSAG, Bristol Social Adjustment Guide.

aConfounders: father’s years in education; multiple birth; BSAG total score at age 7; relation with natural parents at age 7.

bConfounders: multiple birth; BSAG total score at age 7; relation with natural parents at age 7.

cConfounders: father’s years in education; BSAG total score at age 11; relation with natural parents at age 11.

dConfounders: multiple birth; BSAG total score at age 11; relation with natural parents at age 11.