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. 2014 Jan 8;9(1):e82331. doi: 10.1371/journal.pone.0082331

Figure 6. Inhibition of brain tumor growth by 2B3-101 in mice with experimental glioblastoma.

Figure 6

Animals (n = 9 per group) received once-weekly IV administrations of saline, 2B3-101, pegylated liposomal doxorubicin (PEG-lipo-DOX) or free doxorubicin (free DOX), all at a 5 mg/kg doxorubicin equivalent. The study was ended at the pre-set study endpoint. Brain tumor growth was measured by bioluminescence (BLI). Arrows indicate IV injections. *P<0.05 2B3-101 vs pegylated liposomal doxorubicin (PEG-lipo-DOX); **P<0.01 2B3-101 vs saline (two-way ANOVA on Log%BLI).