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. Author manuscript; available in PMC: 2014 Jul 6.
Published in final edited form as: Annu Rev Pharmacol Toxicol. 2013 Oct 16;54:10.1146/annurev-pharmtox-011613-135923. doi: 10.1146/annurev-pharmtox-011613-135923
Figure 2. Modulation of drug pharmacokinetic by the circadian clock.
All rhythmic parameters influencing drug transport and metabolism are highlighted in red. Characteristic functions of the circadian clock on these process are indicated in the respective organs.