Table 1. Biochemical features of the intrahepatic cholestasis of pregnancy (ICP) cases.
N | Gestation at Diagnosis (weeks + days) | Gestation at Delivery (weeks + days) | Duration of Treatment (weeks + days) | Peak BA* (µmol/L) | Peak AST* (IU/L) | Peak ALT* (IU/L) | |
Untreated | 18 | 34+5 (30+2–36+0) | 37+3 (36+3–38+1) | n/a | 29 (22–42) | 68 (38.5–146.5) | 133 (77–185) |
Treated | 46 | 35+0 (29+4–37+0) | 37+2 (36+0–37+5) | 4+6 (3+4–6+6) | 44 (21–79) | 71 (53.5–146.5) | 144 (93.5–262) |
Serum biochemistry measurements represent the peak concentrations measured during the pregnancy.
BA – bile acids (normal range <14 µmol/L); AST – aspartate transaminase (normal range 5–31 IU/L); ALT – alanine transaminase (normal range 5–31 IU/L); n/a – not applicable.
Values represent median and interquartile ranges.