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. 2014 Jan 8;9(1):e83828. doi: 10.1371/journal.pone.0083828

Table 1. Biochemical features of the intrahepatic cholestasis of pregnancy (ICP) cases.

N Gestation at Diagnosis (weeks + days) Gestation at Delivery (weeks + days) Duration of Treatment (weeks + days) Peak BA* (µmol/L) Peak AST* (IU/L) Peak ALT* (IU/L)
Untreated 18 34+5 (30+2–36+0) 37+3 (36+3–38+1) n/a 29 (22–42) 68 (38.5–146.5) 133 (77–185)
Treated 46 35+0 (29+4–37+0) 37+2 (36+0–37+5) 4+6 (3+4–6+6) 44 (21–79) 71 (53.5–146.5) 144 (93.5–262)

Serum biochemistry measurements represent the peak concentrations measured during the pregnancy.

BA – bile acids (normal range <14 µmol/L); AST – aspartate transaminase (normal range 5–31 IU/L); ALT – alanine transaminase (normal range 5–31 IU/L); n/a – not applicable.

Values represent median and interquartile ranges.