Figure 2. Quantification of bacterial load in tissue from healthy and breast cancer patients.
A) Copy numbers of the bacterial 16S gene were compared among healthy (age-matched) (n = 23), paired normal (n = 39) and tumor tissue (n = 39). Healthy specimens were obtained from patients undergoing reduction mammoplasty, with no evidence of breast cancer. Statistical analysis was performed using Kruskal-Wallis nonparametric ANOVA with Dunn’s Multiple Comparison post-test. B) Bacterial load in tissue according to clinical staging of the tumor specimen. Statistical analysis was performed using Cuzick’s Trend test. All statistical analyses were considered significant when P<0.05. Data represent the average of duplicate values. Error bars represent mean ± s.e.m.
