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. 2014 Jan 8;9(1):e83783. doi: 10.1371/journal.pone.0083783

Table 2. Persons affected by the most frequently co-occurring pairs of chronic diseases and their observed and expected prevalence per 100 population.

Frequent co-occurring pairs n Prevalence/100 Chi2 (p value)B Odds Ratio (from Logistic regression) (95% CI)
Observed ExpectedA Observed/Expected Crude Adjusted
HBP and Arthritis 826 18.05 15.62 1.16 9.8 (<0.01) 1.5 (1.4–1.7) 1.4 (1.2–1.6)
HBP and Cancer 401 8.77 8.49 1.03 0.2 (0.63) 1.1 (0.9–1.2) 0.9 (0.8–1.1)
HBP and Heart disease 381 8.33 7.08 1.18 5.0 (0.02) 1.5 (1.2–1.7) 1.1 (0.9–1.3)
Asthma/hayfever and arthritis 367 8.02 5.90 1.36 15.9 (<0.01) 1.9 (1.6–2.2) 1.6 (1.4–1.9)
HBP and Diabetes 365 7.98 5.51 1.45 22.2 (<0.01) 2.5 (2.1–3.1) 2.4 (2.0–2.9)
HBP and Asthma/hayfever 348 7.61 7.56 1.01 0.01 (0.94) 1.0 (0.9–1.2) 1.0 (0.8–1.2)
Cancer and Arthritis 319 6.97 6.62 1.05 0.44 (0.51) 1.1 (0.9–1.3) 1.0 (0.8–1.2)
Arthritis and DepressionC 307 6.71 4.77 1.41 16.0 (<0.01) 2.0 (1.7–2.4) 1.9 (1.6–2.3)
HBP and DepressionC 304 6.65 6.11 1.09 1.1 (0.28) 1.2 (1.0–1.4) 1.2 (1.0–1.5)
Heart disease and Arthritis 284 6.21 5.51 1.13 2.0 (0.15) 1.2 (1.1–1.5) 1.1 (0.9–1.3)
Arthritis and Osteoporosis 257 5.62 4.05 1.39 12.3 (<0.01) 1.9 (1.6–2.3) 1.3 (1.1–1.6)

A Multiplication of observed prevalences of individual disease;

B Test of independence for observed and expected prevalences;

C including anxiety.