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. 2013 Dec 9;7(1):204–212.

Figure 4.

Figure 4

Representative immunostaining patterns according to patient progression-free survival (PFS). A, C: Organic cation transporter 2 (OCT2). B, D: Pan-cytokeratin. Pan-cytokeratin immunostaining enabled clear visualization of tumor budding (TB). A, B: Immunohistochemical results of a tumor from a patient with a long PFS (14.1 months), showing the most favorable OCT2/TB pattern (high OCT2/low TB). C, D: Immunohistochemical results of a tumor from a patient with a short PFS (7.0 months), showing the least favorable pattern (low OCT2/high TB). Scale bar, 100 μm.