Table 1.

Clinicopathological findings of mCRC patients and their association with OCT2 and TB levels

Variables	n	OCT2			TB
		Low	High	P value	Low	High	P value
Age (years)
<60	26	12	14	0.63	14	12	0.81
≥60	54	21	33		26	28
Gender
Male	53	23	30	0.64	28	25	0.64
Female	27	10	17		12	15
Location of primary tumor
Colon	56	25	31	0.46	28	28	1.00
Rectum	24	8	16		12	12
Histological differentiation
Well/moderate	75	31	44	1.00	38	37	1.00
Poor/mucinous	5	2	3		2	3
Depth of invasion
pT2/pT3	41	22	19	0.03*	24	17	0.18
pT4	39	11	28		16	23
Lymph node metastasis
pN0/pN1	45	18	27	0.82	24	21	0.65
pN2	35	15	20		16	19
Lymphatic invasion
ly0/ly1	19	6	13	0.43	14	5	0.03*
ly2/ly3	61	27	34		26	35
Venous invasion
v0/v1	23	7	16	0.32	14	9	0.32
v2/v3	57	26	31		26	31

^*Statistically significant;

mCRC, metastatic colorectal cancer; OCT2, organic cation transporter 2; TB, tumor budding.