Table 2.

Prognostic factors in Cox proportional hazards model

Variable	Univariate analysis			Multivariate analysis
	Risk ratio	95% CI	P	Risk ratio	95% CI	P
Gender	0.917	0.642-1.693	0.742
Male vs Female
Age (years)	1.478	0.789-2.254	0.273
≥62 vs <62
Tumor multiplicity	0.946	0.627-1.751	0.633
Unifocal vs Multifocal
Tumor stage	3.212	2.671-4.754	0.146
≥T1 vs <T1
Histological grade	4.371	2.773-7.159	<0.001	2.841	1.944-4.396	<0.001
Low vs High
Lymph node	5.384	4.129-8.479	<0.001	2.463	1.609-4.175	0.018
N1-2 vs N0
Distant metastasis	9.272	3.778-21.314	<0.001	4.114	2.238-7.116	0.023
M1 vs M0
Argonaute 2	3.887	2.765-6.429	0.009	3.273	2.364-5.877	<0.001
high vs low