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. 2014 Jan 8;9(1):e83664. doi: 10.1371/journal.pone.0083664

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© 2014 Apri et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A solid arrow represents a reaction with two kinetic parameters and a dashed arrow represents a reaction with one kinetic parameter. (A) The full network from [25], (B) The optimal network to produce the dynamics of the five target components for any experimental condition in (22).

Inline graphic — A solid arrow represents a reaction with two kinetic parameters and a dashed arrow represents a reaction with one kinetic parameter. (A) The full network from [25], (B) The optimal network to produce the dynamics of the five target components for any experimental condition in (22).