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. 2014 Jan 8;9(1):e83851. doi: 10.1371/journal.pone.0083851

Table 2. Stratified analysis of the GSTM3 polymorphism and HNC risk.

Variables	N^a	AB+BB vs.AA			BB vs.AB+AA			BB vs.AA			AB vs.AA
		OR^d(95% CI^e)	P^b	I²	OR(95% CI)	P^b	I²	OR(95% CI)	P^b	I²	OR(95% CI)	P^b	I²
Total	14	0.82(0.71,0.94)	0.05	42	0.74(0.54,1.00)	0.66	0	0.67(0.49,0.94)	0.54	0	0.84(0.73,0.97)	0.09	35
Ethnicity
Caucasian	13	0.83(0.72,0.95)	0.04	45	0.73(0.51,1.03)	0.57	0	0.69(0.49,0.99)	0.47	0	0.85(0.73,0.98)	0.07	39
African-American	1	0.61(0.26,1.41)	N/A	N/A	0.77(0.42,1.41)	N/A	N/A	0.56(0.23,1.39)	N/A	N/A	0.66(0.26,1.63)	N/A	N/A
Tumor site
Laryngeal	6	0.83(0.60,1.15)	0.04^c	58	0.52(0.30,0.89)	0.24	27	0.50(0.29,0.87)	0.17	37	0.88(0.71,1.08)	0.08	50
Oral	3	0.92(0.65,1.31)	0.56	0	0.79(0.47,1.32)	0.95	0	0.69(0.35,1.34)	0.80	0	0.95(0.66,1.38)	0.67	0
Pharyngeal	2	0.81(0.53,1.22)	0.22	33	1.11(0.47,2.61)	0.76	0	1.02(0.43,2.42)	0.65	0	0.76(0.49,1.20)	0.21	37
Mixed HNC	3	0.77(0.46,1.29)	0.03^c	72	0.88(0.45,1.72)	0.50	0	0.81(0.42,1.59)	0.39	0	0.76(0.46,1.25)	0.04^c	68
Source of control
PB	7	1.06(0.86,1.31)	0.21	29	0.96(0.55,1.69)	0.66	0	0.98(0.56,1.73)	0.60	0	1.07(0.86,1.34)	0.29	19
HB	7	0.67(0.56,0.81)	0.71	0	0.66(0.46,0.95)	0.56	0	0.55(0.37,0.83)	0.62	0	0.70(0.58,0.84)	0.64	0

^a Number of comparisons.

^b Test for heterogeneity.

^c Random-effects model was used when the P-value for heterogeneity test was <0.05, otherwise fixed-effects model was used.

^d OR, odds ratio.

^e CI, confidence interval.