Table 1. Individual concentrations [arbitrary units] of the three main metabolites NAA, choline, and creatine in PD patients and age-matched controls.
Controls (n = 24) | PD patients (n = 21) | p value2 | ||||||
rostral | caudal | p value1 | rostral | caudal | p value1 | rostral | caudal | |
S/N | 9.1±1.5 | 7.9±1.4 | <0.001 | 8.4±2.0 | 7.4±1.8 | <0.001 | 0.085 | 0.178 |
FWHM (ppm) | 0.09±0.02 | 0.09±0.02 | 0.638 | 0.10±0.03 | 0.09±0.03 | 0.028 | 0.033 | 0.817 |
NAA+NAAG | 57.9±10.8 | 49.8±9.6 | <0.001 | 47.7±17.5 | 42.6±13.8 | 0.005 | 0.002 | 0.006 |
GPC+PCh | 5.5±1.2 | 6.5±1.6 | <0.001 | 4.8±2.0 | 5.9±2.1 | <0.001 | 0.034 | 0.114 |
Cr+PCr | 30.3±5.3 | 29.4±6.3 | 0.299 | 28.9±11.4 | 25.9±9.9 | 0.016 | 0.476 | 0.052 |
1 Significance values from paired t-test between the rostral and caudal values within the group.
2 Significance values from two-sample t-test between both groups.