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. Author manuscript; available in PMC: 2014 Jun 6.
Published in final edited form as: Science. 2013 Nov 14;342(6163):10.1126/science.1246232. doi: 10.1126/science.1246232

Fig. 1. RZZ inhibits microtubule attachment formation at kinetochores independently of Aurora B phosphorylation of NDC-80.

Fig. 1

(A) Cartoon depiction of the kinetochore dynein module.

(B) Chromosome segregation phenotypes for the indicated conditions. GFP∷H2b (arrow) and GFP∷γ-tubulin (arrowhead) signals are indicated. Bar, 5 μm.

(C) Plot of spindle pole separation kinetics, which serves as a readout for kinetochore-microtubule attachment formation. Error bars are SEM with a 95% confidence interval.

(D) Chromosome segregation phenotypes for the indicated conditions (see also Fig. S1). Bar, 5 μm.