Fig. 3. Tail-deleted NDC-80 is resistant to regulation by RZZ.
(A) Chromosome segregation phenotypes for the indicated conditions. Bar, 5 μm.
(B) Plot of spindle pole separation kinetics, as in Fig. 1C.
(C) Experimental strategy for analyzing the effect of different ndc-80 transgenes in an ndc-80(tm5271) mutant background (Fig. S5). Graph on the right shows the percentage of homozygous mutant larvae that develop into fertile adults producing viable embryos. In the absence of a transgene, all homozygous mutants arrest as larvae (Fig. S5).
(D) Fate of ndc-80(tm5271) larvae for the indicated conditions. n is the number of homozygous ndc-80(tm5271) worms/larvae analyzed. See also Fig. S5.