Table 1. Polymorphisms of the TRAF5 and TRAF3IP2 genes in ocular Behçet's Disease.
| Gene | SNPs | Genotype | BD n (%) | Control | P value | Pc value | OR (95%CI) |
| Allele | n (%) | n (%) | |||||
| TRAF5 | rs10863888 | AA | 74 (10) | 170 (10.8) | 0.566 | 5.094 | 0.919 (0.689–1.226) |
| AG | 359 (48.6) | 650 (41.3) | 0.001 | 0.009 | 1.343 (1.127–1.601) | ||
| GG | 306 (41.4) | 754 (47.9) | 0.003 | 0.027 | 0.769 (0.644–0.917) | ||
| A | 507 (34.3) | 990 (31.4) | 0.053 | 0.477 | 1.138 (0.998–1.298) | ||
| G | 971 (65.7) | 2158(68.6) | 0.053 | 0.477 | 0.879 (0.771–1.002) | ||
| rs12569232 | CC | 9 (1.2) | 20 (1.2) | 0.893 | 8.037 | 0.947 (0.429–2.090) | |
| CG | 96 (12.6) | 304 (19.0) | 1.20×10−4 | 1.08×10−3 | 0.617 (0.481–0.790) | ||
| GG | 655 (86.2) | 1277(79.8) | 1.56×10−4 | 1.40×10−3 | 1.583 (1.246–2.011) | ||
| C | 114 (7.5) | 344 (10.7) | 4.34×10−4 | 1.30×10−3 | 0.674 (0.540–0.840) | ||
| G | 1406(92.5) | 2858(89.3) | 4.34×10−4 | 1.30×10−3 | 1.484 (1.190–1.852) | ||
| rs6540679 | AA | 58 (7.4) | 81 (5.2) | 0.036 | 0.324 | 1.449 (1.022–2.053) | |
| AG | 355 (45.0) | 497 (31.9) | 4.00×10−10 | 3.60×10−9 | 1.750 (1.467–2.086) | ||
| GG | 376 (47.7) | 982 (62.9) | 1.35×10−12 | 1.22×10−11 | 0.536 (0.451–0.637) | ||
| A | 471 (29.8) | 659 (21.1) | 3.86×10−11 | 1.16×10−10 | 1.589 (1.384–1.824) | ||
| G | 1107(70.2) | 2461(78.9) | 3.86×10−11 | 1.16×10−10 | 0.629 (0.548–0.722) | ||
| TRAF3IP2 | rs13210247 | AA | 539 (88.4) | 1513(95.1) | 1.79×10−8 | 1.61×10−7 | 0.391 (0.280–0.548) |
| AG | 71 (11.6) | 76 (4.8) | 7.83×10−9 | 7.05×10−8 | 2.626 (1.873–3.682) | ||
| GG | 0 (0.0) | 2 (0.1) | 0 | 0 | |||
| A | 1149(94.2) | 3102(97.5) | 6.91×10−8 | 2.07×10−7 | 0.417 (0.301–0.579) | ||
| G | 71 (5.8) | 80 (2.5) | 6.91×10−8 | 2.07×10−7 | 2.396 (1.728–3.322) |
SNP, single-nucleotide polymorphism; VKH, Vogt-Koyanagi-Harada; BD, Behçet's disease; OR, odds ratio; CI, confidence interval; Pc, Bonferroni corrected p value which pc equaled to a p value multiplied by 9 (for genotype) or 3 (for allele).