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. 2014 Jan 8;9(1):e84214. doi: 10.1371/journal.pone.0084214

Table 3. TRAF family gene polymorphisms in autoimmune diseases.

Gene SNP Autoimmune Race P value OR (95%CI)
Disease
TRAF1 [51], [52], [53] rs3761847 SLE Japanese 0.016 1.36 (1.05–1.76)
RA North American 4×10−14 1.30 (1.23–1.42)
& Swedish
RA Japanese 0.031 1.18 (1.01–1.39)
rs7021206 RA Korean 0.0037 1.21 (1.06–1.38)
TRAF6 [54] rs5030445 SLE African American 0.00173 0.68 (0.53–0.87)
rs5030437 SLE African American 0.004456 0.70 (0.54–0.90)
rs5030472 SLE European 0.003342 0.65 (0.49–0.87)
rs5030470 SLE European 0.000179 0.55 (0.40–0.76)
TRAF3IP2 [23], [24], [55], [56] rs33980500 psoriasis German 1.24×10−16 *
PsA German 4.57×10−12 1.95
SLE Italian 0.021 1.71
rs13210247 psoriasis German 2..36×10−10 *
PsA German 5.76×10−7 2.08 (1.61–2.69)
BD Chinese 7.05×10−8 2.63 (1.87–3.68)
VKH Chinese 3.31×10−5 2.18 (1.56–3.05)
rs13190932 PsA German 9.19×10−7 2.19 (1.66–2.88)
UC Italian 0.02 5.05 (1.12–2.83)
CD Italian 0.026 3.03 (1.1–8.3)
rs13196377 PsA German 9.36×10−7 2.17 (1.66–2.88)
SLE Italian 0.002 2.59 (1.39–4.80)
UC Italian 0.049 4.1 (0.91–18.18)
TRAF5 [18] rs10863888 RA UK Caucasian 0.003 1.39 (1.11–1.75)
BD Chinese 0.009 1.34 (1.13–1.60)
rs7514863 RA UK Caucasian 0.005 1.2 (1.06–1.36)

The data not stated in paper.

SLE, Systemic Lupus Erythematosus; RA, Rheumatoid Arthritis; PsA, Psoriatic Arthritis; UC, Ulcerative Colitis; CD, Crohn's Disease.