Table 2. The pooled adverse effects of Methylphenidate in included studies.

Adverse effect	No. of studies	No. of patients Methylphenidate/placebo	Risk Ratio and 95%CI	P value	I2 (%)
Tachycardia	3	96/100	0.66 [0.21, 2.06]	0.47	40
Insomnia	2	128/131	1.46 [0.78, 2.74]	0.23	0
Vertigo	2	128/131	3.74 [1.52, 9.16]	0.004	0
Anxiety	2	145/148	2.50 [1.32, 4.73]	0.005	0
Nausea	2	110/112	4.65 [1.84, 11.77]	0.001	0
Anorexia	2	121/123	2.18 [1.15, 4.14]	0.02	0