Table 1. Distances between skull landmarks on wild-type and Rsk2-/Y mutant mice.

Distances	Mean WT	STD WT	Mean Rsk2 mutants	STD Rsk2 mutants	p-value
Between 1 and 2	7.10	0.59	6.84	0.35	0.03
Between 1 and 3	15.05	0.46	13.92	0.59	0.01
Between 1 and 4	18.59	0.41	17.24	0.57	0.005
Between 1 and 5	21.87	0.49	20.48	0.48	0.005
Between 2 and 3	8.07	0.45	7.25	0.47	0.005
Between 2 and 4	11.72	0.38	10.69	0.45	0.005
Between 2 and 5	15.21	0.35	14.13	0.31	0.005
Between L and R 6	12.08	0.17	12.16	0.13	0.47
Between L and R 7	6.42	0.21	6.45	0.27	0.68
Between L and R 8	4.77	0.11	4.79	0.73	0.22
Between L and R 9	6.27	0.25	6.13	0.12	0.06
Between L and R 10	0.74	0.06	0.71	0.08	0.47
Between L and R 11	1.05	0.05	1.13	0.11	0.29
Between L and R 12	10.08	0.37	10.22	0.28	0.29
Between L and R 15	4.53	0.19	4.72	0.51	0.37
Between L and R 16	2.29	0.22	2.23	0.23	0.57
Between 1 and 6R	15.24	0.34	14.39	0.52	0.008
Between 1 and 6L	15.20	0.32	14.47	0.31	0.008
Between 1 and 7R	7.92	0.28	7.18	0.58	0.008
Between 1 and 7L	7.89	0.22	7.24	0.34	0.005
Between 1 and 8R	6.90	0.24	6.29	0.46	0.88
Between 1 and 8L	6.90	0.25	6.35	0.29	0.68
Between 1 and 9R	20.65	0.47	19.55	0.46	0.008
Between 1 and 9L	20.62	0.48	19.56	0.32	0.008

In bold are distances significantly different between wild- type (WT) and mutants (all these distances were shorter in mutants). Anatomical landmarks are explained in Fig. S1 (supplementary information). All distances are in millimeters. STD: standard deviation; L: left; R: right.