Table 1. Summary of previously published data and present results.
Treatment | Post-treatment | ||||
Time after exposure onset | 12 h | 24 h | 42 h | 48 h | |
Proliferation [15] | - | ▾** | ▾** | ▾* | |
Cell cycle phases [15] | G0/G1 | - | ▴** | - | - |
S | ▴* | ▾* | - | ▾* | |
G2/M | - | - | - | - | |
Cyclin expression [16] | D1 | ▴* | ▴* | ▾* | ND |
A | ▴*** | ▾** | ▾** | ND | |
B1 | - | ▾* | - | ND | |
p27 expression [16] | - | ▴* | ▾** | ND | |
Apoptosis | ND | - | ▴** | ND | |
p53 | ▾*/- | ▴*** | ▾*/- | ND | |
Bcl-2 | ND | ▾** | - | ND |
▴: statistically significant increase; ▾: statistically significant decrease; ND: no data; -: no significant (0.05<p); *: 0.01<p<0.05; **: 0.001≤p≤0.01; ***: p<0.001 (Student's t-test); ▾*/-: statistically significant decrease of active p53 only, no change in total p53 (see Figs. 4A and 5); [15] and [16]: previously published data, see References.