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. 2014 Jan 8;9(1):e84813. doi: 10.1371/journal.pone.0084813

Table 3. Adjusted Associations of Whole Cow's Milk Consumption with CVD Risk Factors in Older Chinese (5853 men and 14,482 women) in Phases 1 and 2 of the Guangzhou Biobank Cohort Study, 2003–2006.

Whole cow's milk consumption (cportions/week) P-value for trend
N 0 1–3 >3
aCVD risk factor bModel Men Women dcoefficient 95% CI coefficient 95% CI
Systolic blood 1 5826 14431 reference 1.59 −2.68, −0.50 3.57 −4.64, −2.50 <0.001
pressure (mm Hg) 2 5445 13422 reference 1.33 −2.47, −0.21 3.28 −4.39, −2.17 <0.001
3 5424 13369 reference 1.10 −2.20, −0.02 2.56 −3.63, −1.49 <0.001
Diastolic blood 1 5825 14430 reference 0.86 −1.43, −0.30 1.83 −2.38, −1.28 <0.001
pressure (mm Hg) 2 5444 13421 reference 0.74 −1.33, −0.16 1.70 −2.28, −1.13 <0.001
3 5423 13368 reference 0.62 −1.18, −0.06 1.32 −1.87, −0.77 <0.001
Pulse pressure 1 5822 14425 reference −0.72 −1.44, 0.01 1.76 −2.47, −1.05 <0.001
(mm Hg) 2 5441 13416 reference −0.65 −1.40, 0.10 1.68 −2.42, −0.94 <0.001
3 5420 13363 reference −0.54 −1.28, 0.20 1.31 −2.04, −0.58 <0.001
HDL-cholesterol 1 5826 14414 reference 0.03 0.01, 0.05 0.03 0.02, 0.05 <0.001
(mmol/L) 2 5447 13407 reference 0.03 0.01, 0.05 0.03 0.01, 0.05 <0.001
3 5414 13334 reference 0.03 0.01, 0.04 0.02 0.01, 0.04 0.002
LDL-cholesterol 1 5812 14370 reference 0.02 −0.01, 0.05 0.03 −0.003, 0.05 0.042
(mmol/L) 2 5433 13364 reference 0.02 −0.01, 0.05 0.02 −0.01, 0.05 0.17
3 5400 13291 reference 0.02 −0.01, 0.05 0.02 −0.01, 0.05 0.08
Triglycerides 1 5827 14419 reference 0.09 −0.14, −0.03 0.10 −0.15, −0.04 <0.001
(mmol/L) 2 5448 13411 reference 0.09 −0.14, −0.03 0.09 −0.15, −0.04 <0.001
3 5415 13338 reference 0.08 −0.13, −0.02 0.06 −0.11, −0.002 0.009
Fasting plasma 1 5806 14384 reference −0.02 −0.09, 0.06 0.05 −0.03, 0.12 0.34
glucose (mmol/L) 2 5424 13379 reference 0.003 −0.08, 0.08 0.05 −0.03, 0.13 0.24
3 5394 13306 reference 0.01 −0.07, 0.09 0.08 0.01, 0.16 0.048
Body mass index 1 5825 14440 reference −0.10 −0.24, 0.04 0.31 −0.45, −0.17 <0.001
2 5453 13430 reference −0.07 −0.21, 0.08 0.26 −0.40, −0.11 <0.001
Waist-hip ratio 1 5822 14419 reference 0.003 −0.01, −0.001 0.01 −0.01, −0.006 <0.001
2 5442 13409 reference −0.002 −0.004, 0.001 0.01 −0.01, −0.003 <0.001
OR 95% CI OR 95% CI
Diabetes 1 5818 14418 reference 0.98 0.86, 1.12 1.07 0.95, 1.21 0.35
2 5437 13410 reference 0.98 0.85, 1.12 1.04 0.91, 1.18 0.67
3 5403 13334 reference 0.99 0.86, 1.13 1.09 0.96, 1.24 0.24
a

Censored regression was used for systolic blood pressure, diastolic blood pressure, pulse pressure, HDL, LDL, triglyceride and fasting plasma glucose; linear regression was used for body mass index and waist-hip ratio; logistic regression was used for diabetes.

b

Model 1 adjusted for age, sex and phase; Model 2 adjusted for age, sex, phase, SEP (education, father's occupation, longest-held occupation and personal income) and lifestyle (smoking status, alcohol use and physical activity); Model 3 adjusted for age, sex, phase, SEP, lifestyle, BMI and WHR.

c

1 portion = 250 ml.

d

Coefficient means changes in risk factors; bold values indicate P<0.05.