Table 3. Adjusted Associations of Whole Cow's Milk Consumption with CVD Risk Factors in Older Chinese (5853 men and 14,482 women) in Phases 1 and 2 of the Guangzhou Biobank Cohort Study, 2003–2006.
Whole cow's milk consumption (cportions/week) | P-value for trend | ||||||||
N | 0 | 1–3 | >3 | ||||||
aCVD risk factor | bModel | Men | Women | dcoefficient | 95% CI | coefficient | 95% CI | ||
Systolic blood | 1 | 5826 | 14431 | reference | −1.59 | −2.68, −0.50 | −3.57 | −4.64, −2.50 | <0.001 |
pressure (mm Hg) | 2 | 5445 | 13422 | reference | −1.33 | −2.47, −0.21 | −3.28 | −4.39, −2.17 | <0.001 |
3 | 5424 | 13369 | reference | −1.10 | −2.20, −0.02 | −2.56 | −3.63, −1.49 | <0.001 | |
Diastolic blood | 1 | 5825 | 14430 | reference | −0.86 | −1.43, −0.30 | −1.83 | −2.38, −1.28 | <0.001 |
pressure (mm Hg) | 2 | 5444 | 13421 | reference | −0.74 | −1.33, −0.16 | −1.70 | −2.28, −1.13 | <0.001 |
3 | 5423 | 13368 | reference | −0.62 | −1.18, −0.06 | −1.32 | −1.87, −0.77 | <0.001 | |
Pulse pressure | 1 | 5822 | 14425 | reference | −0.72 | −1.44, 0.01 | −1.76 | −2.47, −1.05 | <0.001 |
(mm Hg) | 2 | 5441 | 13416 | reference | −0.65 | −1.40, 0.10 | −1.68 | −2.42, −0.94 | <0.001 |
3 | 5420 | 13363 | reference | −0.54 | −1.28, 0.20 | −1.31 | −2.04, −0.58 | <0.001 | |
HDL-cholesterol | 1 | 5826 | 14414 | reference | 0.03 | 0.01, 0.05 | 0.03 | 0.02, 0.05 | <0.001 |
(mmol/L) | 2 | 5447 | 13407 | reference | 0.03 | 0.01, 0.05 | 0.03 | 0.01, 0.05 | <0.001 |
3 | 5414 | 13334 | reference | 0.03 | 0.01, 0.04 | 0.02 | 0.01, 0.04 | 0.002 | |
LDL-cholesterol | 1 | 5812 | 14370 | reference | 0.02 | −0.01, 0.05 | 0.03 | −0.003, 0.05 | 0.042 |
(mmol/L) | 2 | 5433 | 13364 | reference | 0.02 | −0.01, 0.05 | 0.02 | −0.01, 0.05 | 0.17 |
3 | 5400 | 13291 | reference | 0.02 | −0.01, 0.05 | 0.02 | −0.01, 0.05 | 0.08 | |
Triglycerides | 1 | 5827 | 14419 | reference | −0.09 | −0.14, −0.03 | −0.10 | −0.15, −0.04 | <0.001 |
(mmol/L) | 2 | 5448 | 13411 | reference | −0.09 | −0.14, −0.03 | −0.09 | −0.15, −0.04 | <0.001 |
3 | 5415 | 13338 | reference | −0.08 | −0.13, −0.02 | −0.06 | −0.11, −0.002 | 0.009 | |
Fasting plasma | 1 | 5806 | 14384 | reference | −0.02 | −0.09, 0.06 | 0.05 | −0.03, 0.12 | 0.34 |
glucose (mmol/L) | 2 | 5424 | 13379 | reference | 0.003 | −0.08, 0.08 | 0.05 | −0.03, 0.13 | 0.24 |
3 | 5394 | 13306 | reference | 0.01 | −0.07, 0.09 | 0.08 | 0.01, 0.16 | 0.048 | |
Body mass index | 1 | 5825 | 14440 | reference | −0.10 | −0.24, 0.04 | −0.31 | −0.45, −0.17 | <0.001 |
2 | 5453 | 13430 | reference | −0.07 | −0.21, 0.08 | −0.26 | −0.40, −0.11 | <0.001 | |
Waist-hip ratio | 1 | 5822 | 14419 | reference | −0.003 | −0.01, −0.001 | −0.01 | −0.01, −0.006 | <0.001 |
2 | 5442 | 13409 | reference | −0.002 | −0.004, 0.001 | −0.01 | −0.01, −0.003 | <0.001 | |
OR | 95% CI | OR | 95% CI | ||||||
Diabetes | 1 | 5818 | 14418 | reference | 0.98 | 0.86, 1.12 | 1.07 | 0.95, 1.21 | 0.35 |
2 | 5437 | 13410 | reference | 0.98 | 0.85, 1.12 | 1.04 | 0.91, 1.18 | 0.67 | |
3 | 5403 | 13334 | reference | 0.99 | 0.86, 1.13 | 1.09 | 0.96, 1.24 | 0.24 |
Censored regression was used for systolic blood pressure, diastolic blood pressure, pulse pressure, HDL, LDL, triglyceride and fasting plasma glucose; linear regression was used for body mass index and waist-hip ratio; logistic regression was used for diabetes.
Model 1 adjusted for age, sex and phase; Model 2 adjusted for age, sex, phase, SEP (education, father's occupation, longest-held occupation and personal income) and lifestyle (smoking status, alcohol use and physical activity); Model 3 adjusted for age, sex, phase, SEP, lifestyle, BMI and WHR.
1 portion = 250 ml.
Coefficient means changes in risk factors; bold values indicate P<0.05.