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. Author manuscript; available in PMC: 2014 Jan 8.
Published in final edited form as: Arch Ophthalmol. 2012 Nov;130(11):10.1001/archophthalmol.2012.1971. doi: 10.1001/archophthalmol.2012.1971

Table 1. ADNIV Stages of disease and associated clinical findings.

Stage Anterior Segment Posterior Segment Electroretinogram
Stage I Rare cells Rare cells Reduced b-wave
Stage II Mild cells
Mild posterior subcapsular cataract
Moderate cells
Optic disc edema
Cystoid macular edema
Peripheral pigmentation of the retina
Flat b-wave, normal a-wave
Stage III Moderate cells
Anterior subcapsular cataract
Moderate posterior subcapsular cataract
Iris synechiae
Moderate cells
Vitreous traction at posterior pole
Epiretinal membrane
Tractional retinal detachment
Posterior vitreous bands
Peripheral fibrosis
Peripheral neovascularization
Neovascularization of the disc
Pigmentary retinopathy
Cystoid macular edema
Flat b-wave, reduced a-wave
Stage IV Iris bombe, seclusio pupil
Peripheral anterior synechiae
Angle closure glaucoma
Neovascular glaucoma
Moderate cells
Vitreous hemorrhage
Posterior tractional retinal detachment
Anterior tractional retinal detachment
Non-recordable ERG
Stage V Phthisis Combined tractional and rhegmatogenous retinal detachment
Phthisis

ERG, Electroretinogram