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. 2014 Jan 8;9(1):e85009. doi: 10.1371/journal.pone.0085009

Figure 4. Anxiolytic-like effect of exogenous Lipoxin A4 in the EPM test.

Figure 4

After a single dose of Lipoxin A4 (10 ug/kg, i.p.), adult Swiss mice showed a significant increase in (A) open arm time. No difference was observed in (B) entries in open arms, (C) time in closed arms or (D) entries in closed arms. Data are presented as mean ± SEM (n = 9). Statistical Analysis was performed by ANOVA followed by Newman-Keuls post hoc test. *p<0.05 vs vehicle.