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. 2014 Jan 8;9(1):e85068. doi: 10.1371/journal.pone.0085068

Table 3. Association of metabolic syndrome and its components with age-related cataract by gender.

Variables Total cataract Cortical subtype Nuclear subtype
Model1 Model2 Model1 Model2 Model1 Model2
OR(95% CI) P OR(95% CI) P OR(95% CI) P OR(95% CI) P OR(95% CI) P OR(95% CI) P
Male
MetS (presence vs. absence) 1.00(0.83,1.20) 0.973 0.95(0.79,1.14) 0.548 0.93(0.67,1.29) 0.646 0.90(0.63,1.26) 0.543 1.13(0.89,1.43) 0.331 1.07(0.85,1.34) 0.572
Number of MetS components
0–1 1 1 1 1 1 1
2 1.15(0.90,1.46) 1.11(0.87,1.43) 1.19(0.84,1.70) 1.16(0.82,1.63) 1.08(0.78,1.48) 1.04(0.74,1.44)
3 1.11(0.87,1.40) 1.05(0.82,1.34) 0.89(0.58,1.36) 0.86(0.55,1.34) 1.25(0.92,1.70) 1.17(0.86,1.60)
4–5 1.00(0.77,1.30) 0.92(0.71,1.20) 1.10(0.71,1.72) 1.06(0.67,1.67) 1.06(0.74,1.52) 0.99(0.71,1.39)
P for trend 0.885 0.634 0.93 0.907 0.463 0.767
MetS component
High waist circumference 1.02(0.85,1.23) 0.830 0.95(0.80,1.15) 0.615 0.83(0.58,1.18) 0.288 0.84(0.59,1.21) 0.323 1.23(0.97,1.55) 0.082 1.14(0.91,1.42) 0.264
Low HDL 0.99(0.83,1.19) 0.944 0.01(0.84,1.22) 0.888 0.90(0.66,1.22) 0.485 0.93(0.68,1.27) 0.791 1.06(0.83,1.34) 0.659 1.09(0.85,1.39) 0.519
High glucose 1.03(0.86,1.22) 0.757 1.01(0.85,1.20) 0.949 0.94(0.69,1.28) 0.685 0.90(0.66,1.24) 0.521 1.14(0.91,1.43) 0.245 1.14(0.92,1.41) 0.248
High triglycerides 1.00(0.83,1.19) 0.963 0.95(0.80,1.14) 0.611 1.19(0.87,1.62) 0.278 1.11(0.82,1.52) 0.543 0.97(0.78,1.22) 0.817 0.95(0.76,1.18) 0.637
High blood pressure 1.04(0.86,1.26) 0.692 1.00(0.82,1.22) 0.990 1.27(0.93,1.72) 0.133 1.24(0.92,1.69) 0.180 0.92(0.71,1.18) 0.511 0.87(0.68,1.12) 0.278
Female
MetS (presence vs. absence) 1.21(1.01,1.46) 0.036 1.24(1.03,1.49) 0.030 0.84(0.62,1.14) 0.274 0.89(0.66,1.19) 0.430 1.23(1.01,1.50) 0.048 1.24(1.01,1.54) 0.046
Number of MetS components
0–1 1 1 1 1 1 1
2 1.19(0.93,1.53) 1.23(0.94,1.61) 0.85(0.56,1.30) 0.91(0.59,1.40) 1.17(0.85,1.59) 1.20(0.86,1.68)
3 1.24(0.99,1.55) 1.25(0.98,1.60) 0.62(0.43,0.91) 0.67(0.46,0.96) 1.33(1.01,1.75) 1.34(1.01,1.80)
4–5 1.39(1.08,1.80) 1.47(1.12,1.93) 0.94(0.61,1.44) 1.03(0.67,1.58) 1.30(0.96,1.76) 1.37(0.99,1.90)
P for trend 0.011 0.007 0.503 0.797 0.046 0.037
MetS component
High waist circumference 1.09(0.90,1.32) 0.388 1.11(0.91,1.36) 0.297 0.75(0.55,1.00) 0.051 0.78(0.57,1.06) 0.115 1.12(0.88,1.41) 0.364 1.15(0.90,1.48) 0.270
Low HDL 1.27(1.08,1.50) 0.005 1.26(1.07,1.49) 0.006 1.15(0.87,1.52) 0.318 1.14(0.87,1.50) 0.336 1.26(1.04,1.52) 0.018 1.24(1.02,1.50) 0.031
High glucose 1.19(0.98,1.43) 0.065 1.23(1.02,1.49) 0.030 0.98(0.72,1.34) 0.903 1.01(0.74,1.39) 0.952 1.13(0.90,1.41) 0.294 1.20(0.95,1.51) 0.132
High triglycerides 1.20(0.99,1.44) 0.052 1.26(1.04,1.52) 0.020 1.03(0.76,1.39) 0.842 1.12(0.84,1.50) 0.442 1.14(0.92,1.40) 0.236 1.18(0.95,1.46) 0.140
High blood pressure 1.03(0.86,1.24) 0.755 1.08(0.89,1.30) 0.463 0.99(0.74,1.31) 0.932 1.07(0.80,1.42) 0.614 1.00(0.81,1.24) 0.992 1.03(0.83,1.29) 0.772

Data are presented as the odds ratio (95% confidence interval).Abbreviation: MetS, Metabolic syndrome; HDL, high density lipoprotein cholesterol.

Model 1: adjusted by age and survey year; model 2: adjusted by socioeconomic and lifestyle-related characteristics including income, education, residential area, smoking status, drinking alcohol, exercise, occupation (farmer or fisher), family history of eye disease, and sun exposure.