Table 3. Association of metabolic syndrome and its components with age-related cataract by gender.
Variables | Total cataract | Cortical subtype | Nuclear subtype | |||||||||
Model1 | Model2 | Model1 | Model2 | Model1 | Model2 | |||||||
OR(95% CI) | P | OR(95% CI) | P | OR(95% CI) | P | OR(95% CI) | P | OR(95% CI) | P | OR(95% CI) | P | |
Male | ||||||||||||
MetS (presence vs. absence) | 1.00(0.83,1.20) | 0.973 | 0.95(0.79,1.14) | 0.548 | 0.93(0.67,1.29) | 0.646 | 0.90(0.63,1.26) | 0.543 | 1.13(0.89,1.43) | 0.331 | 1.07(0.85,1.34) | 0.572 |
Number of MetS components | ||||||||||||
0–1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||
2 | 1.15(0.90,1.46) | 1.11(0.87,1.43) | 1.19(0.84,1.70) | 1.16(0.82,1.63) | 1.08(0.78,1.48) | 1.04(0.74,1.44) | ||||||
3 | 1.11(0.87,1.40) | 1.05(0.82,1.34) | 0.89(0.58,1.36) | 0.86(0.55,1.34) | 1.25(0.92,1.70) | 1.17(0.86,1.60) | ||||||
4–5 | 1.00(0.77,1.30) | 0.92(0.71,1.20) | 1.10(0.71,1.72) | 1.06(0.67,1.67) | 1.06(0.74,1.52) | 0.99(0.71,1.39) | ||||||
P for trend | 0.885 | 0.634 | 0.93 | 0.907 | 0.463 | 0.767 | ||||||
MetS component | ||||||||||||
High waist circumference | 1.02(0.85,1.23) | 0.830 | 0.95(0.80,1.15) | 0.615 | 0.83(0.58,1.18) | 0.288 | 0.84(0.59,1.21) | 0.323 | 1.23(0.97,1.55) | 0.082 | 1.14(0.91,1.42) | 0.264 |
Low HDL | 0.99(0.83,1.19) | 0.944 | 0.01(0.84,1.22) | 0.888 | 0.90(0.66,1.22) | 0.485 | 0.93(0.68,1.27) | 0.791 | 1.06(0.83,1.34) | 0.659 | 1.09(0.85,1.39) | 0.519 |
High glucose | 1.03(0.86,1.22) | 0.757 | 1.01(0.85,1.20) | 0.949 | 0.94(0.69,1.28) | 0.685 | 0.90(0.66,1.24) | 0.521 | 1.14(0.91,1.43) | 0.245 | 1.14(0.92,1.41) | 0.248 |
High triglycerides | 1.00(0.83,1.19) | 0.963 | 0.95(0.80,1.14) | 0.611 | 1.19(0.87,1.62) | 0.278 | 1.11(0.82,1.52) | 0.543 | 0.97(0.78,1.22) | 0.817 | 0.95(0.76,1.18) | 0.637 |
High blood pressure | 1.04(0.86,1.26) | 0.692 | 1.00(0.82,1.22) | 0.990 | 1.27(0.93,1.72) | 0.133 | 1.24(0.92,1.69) | 0.180 | 0.92(0.71,1.18) | 0.511 | 0.87(0.68,1.12) | 0.278 |
Female | ||||||||||||
MetS (presence vs. absence) | 1.21(1.01,1.46) | 0.036 | 1.24(1.03,1.49) | 0.030 | 0.84(0.62,1.14) | 0.274 | 0.89(0.66,1.19) | 0.430 | 1.23(1.01,1.50) | 0.048 | 1.24(1.01,1.54) | 0.046 |
Number of MetS components | ||||||||||||
0–1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||
2 | 1.19(0.93,1.53) | 1.23(0.94,1.61) | 0.85(0.56,1.30) | 0.91(0.59,1.40) | 1.17(0.85,1.59) | 1.20(0.86,1.68) | ||||||
3 | 1.24(0.99,1.55) | 1.25(0.98,1.60) | 0.62(0.43,0.91) | 0.67(0.46,0.96) | 1.33(1.01,1.75) | 1.34(1.01,1.80) | ||||||
4–5 | 1.39(1.08,1.80) | 1.47(1.12,1.93) | 0.94(0.61,1.44) | 1.03(0.67,1.58) | 1.30(0.96,1.76) | 1.37(0.99,1.90) | ||||||
P for trend | 0.011 | 0.007 | 0.503 | 0.797 | 0.046 | 0.037 | ||||||
MetS component | ||||||||||||
High waist circumference | 1.09(0.90,1.32) | 0.388 | 1.11(0.91,1.36) | 0.297 | 0.75(0.55,1.00) | 0.051 | 0.78(0.57,1.06) | 0.115 | 1.12(0.88,1.41) | 0.364 | 1.15(0.90,1.48) | 0.270 |
Low HDL | 1.27(1.08,1.50) | 0.005 | 1.26(1.07,1.49) | 0.006 | 1.15(0.87,1.52) | 0.318 | 1.14(0.87,1.50) | 0.336 | 1.26(1.04,1.52) | 0.018 | 1.24(1.02,1.50) | 0.031 |
High glucose | 1.19(0.98,1.43) | 0.065 | 1.23(1.02,1.49) | 0.030 | 0.98(0.72,1.34) | 0.903 | 1.01(0.74,1.39) | 0.952 | 1.13(0.90,1.41) | 0.294 | 1.20(0.95,1.51) | 0.132 |
High triglycerides | 1.20(0.99,1.44) | 0.052 | 1.26(1.04,1.52) | 0.020 | 1.03(0.76,1.39) | 0.842 | 1.12(0.84,1.50) | 0.442 | 1.14(0.92,1.40) | 0.236 | 1.18(0.95,1.46) | 0.140 |
High blood pressure | 1.03(0.86,1.24) | 0.755 | 1.08(0.89,1.30) | 0.463 | 0.99(0.74,1.31) | 0.932 | 1.07(0.80,1.42) | 0.614 | 1.00(0.81,1.24) | 0.992 | 1.03(0.83,1.29) | 0.772 |
Data are presented as the odds ratio (95% confidence interval).Abbreviation: MetS, Metabolic syndrome; HDL, high density lipoprotein cholesterol.
Model 1: adjusted by age and survey year; model 2: adjusted by socioeconomic and lifestyle-related characteristics including income, education, residential area, smoking status, drinking alcohol, exercise, occupation (farmer or fisher), family history of eye disease, and sun exposure.