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. 2014 Jan 8;9(1):e85581. doi: 10.1371/journal.pone.0085581

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© 2014 Antonson et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) 13 weeks old aP2-Cre/ERα^flox/flox mice treated with vehicle have swollen abdomen while littermates treated with Letrozole for 17 days looks normal (B). (C) Uterus from vehicle treated aP2−/ERα^flox/flox mice with severe hydrometra. (D) Uterus from Letrozole treated aP2-Cre/ERα^flox/flox mice looks normal.