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Adverse effects associated with high-energy N-TIRE in Dog 5. (A) Right unilateral transtentorial herniation resulting in mesencephalic compression (black arrows) in the most caudal aspect of the N-TIRE-affected area (white arrowheads). (B) Cerebrocortical necrosis associated with marked vascular disruption and large artery thrombosis in the N-TIRE treatment region (H&E). Scale bars = 2.0 mm (B), 1cm (A).
