Figure 4. The majority of gp250-selected MCC-specific CD4⁺ T cells express Vα11⁺ TCR.

(A and B) The Vα11 expression of MCC-tetramer⁺ peripheral CD4⁺ T cells in B6.K or gp250 SC mice. (B) n = 6; mean ± SD; two-tailed Mann–Whitney test. (C and D) The CD69 upregulation of sorted MCC-tetramer⁻ or MCC-tetramer⁺ CD4⁺ T cells from B6.K or gp250 SC splenocytes. Data are representative of three experiments. (D): n = 3, paired t tests.

DOI: http://dx.doi.org/10.7554/eLife.01457.007