Figure 3.
Association of GILT expression with survival is independent of COO classification. (A) The relative mRNA expression of GILT in patients classified as GCB or ABC subtype in the four cohorts. Each symbol represents an individual patient. Comparison of GILT expression in GCB and ABC subtypes using a two sample independent t-test revealed p = 0.0003 in the Lenz CHOP, p = 0.0179 in the Hummel CHOP, p = 0.0653 in the Lenz R-CHOP, and p = 0.2887 in the Shaknovich R-CHOP cohort. The line and error bars indicate the mean ± SEM (*p < 0.05). (B) Adjusted for COO subtype, the hazard ratio, 95% confidence interval and p-value comparing survival of patients with ≤10 to >10% expression of GILT in each cohort.
